GVHD: ferocity affects feracitas

GVHD: ferocity affects feracitas.

For young patients preparing for autologous and allogeneic stem cell transplantation (SCT), infertility is a major concern that has been attributed to myeloablative conditioning, which involves the use of robust systemic regimens such as chemotherapy and total body irradiation. To preserve gonadal function, we are beginning to explore the utility of “reduced-intensity conditioning” regimens. Fu...

Interferon-λ: Inters Ferocity or Inter-Ferocities?

[7] . Though the role of IFN-λ in the context of these conditions has been discussed previously [8–10] , much more research is required to completely understand its physiological and pathological impact. Here, the articles by Koch and Finotto [11] , Griffiths et al. [12] , Stiff and Carson [13] and Mihm [14] aim to shed light on the different functions of IFN-λ. Together, these review articles ...

Recipient NOD2/CARD15 status affects cellular infiltrates in human intestinal GvHD

Background: NOD2/CARD15 polymorphisms have been identified as risk factors of both, Crohn ́s disease and graft versus host disease (GvHD) following allogeneic stem cell transplantation. However, the role of these receptors of innate immunity in the pathophysiology of gastrointestinal GvHD is still poorly defined. Methods: Immunohistological features of intestinal GvHD were analyzed in gastrointe...

[Post-transfusion GVHD].

The Japanese Red Cross Society has appointed representatives to Blood Centers nationwide to collect information on blood transfusion-associated adverse reactions, and data on 310 suspected cases of post-transfusion GVHD were collected during the 8-year period from 1993 to 2000. A diagnosis of posttransfusion GVHD was made in 61 cases based on the demonstrated presence of donor lymphocytes in th...

Rare cells predict GVHD.